brain disease breakdown circulatory collapse collapse crack-up crackup emotional disorder emotional instability exhaustion frayed nerves frazzled nerves functional nervous disorder insanity jangled nerves maladjustment manic-depressive psychosis melancholia mental disorder mental illness nervous disorder nervous exhaustion nervous prostration neurasthenia neurosis paranoia personality disorder problems in living prostration psychosis raw nerves reaction schizophrenia shattered nerves social maladjustment twanging nerves